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( A ) Schematic diagram of patients with ESRD receiving intradialysis light aerobic exercise training ( n = 3 patients per group) or a nonexercise lifestyle ( n = 3 patients per group) for 12 weeks. An adjustable, bed-mounted treadmill was used as the training method. ( B ) Serum circulating irisin levels in resting or exercise-trained patients with ESRD at week 0 and week 12 ( n = 3 patients per group). ( C ) Representative dual-energy <t>x-ray</t> <t>absorptiometry</t> images of lumbar in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 vertebral <t>BMD</t> and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). ( D ) Representative dual-energy x-ray absorptiometry images of femur in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 femoral BMD and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). Data were analyzed by 2-way ANOVA ( B – D ). * P < 0.05; ** P < 0.01; *** P < 0.001. Data were presented as mean ± SD.
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( A ) Schematic diagram of patients with ESRD receiving intradialysis light aerobic exercise training ( n = 3 patients per group) or a nonexercise lifestyle ( n = 3 patients per group) for 12 weeks. An adjustable, bed-mounted treadmill was used as the training method. ( B ) Serum circulating irisin levels in resting or exercise-trained patients with ESRD at week 0 and week 12 ( n = 3 patients per group). ( C ) Representative dual-energy <t>x-ray</t> <t>absorptiometry</t> images of lumbar in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 vertebral <t>BMD</t> and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). ( D ) Representative dual-energy x-ray absorptiometry images of femur in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 femoral BMD and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). Data were analyzed by 2-way ANOVA ( B – D ). * P < 0.05; ** P < 0.01; *** P < 0.001. Data were presented as mean ± SD.
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( A ) Schematic diagram of patients with ESRD receiving intradialysis light aerobic exercise training ( n = 3 patients per group) or a nonexercise lifestyle ( n = 3 patients per group) for 12 weeks. An adjustable, bed-mounted treadmill was used as the training method. ( B ) Serum circulating irisin levels in resting or exercise-trained patients with ESRD at week 0 and week 12 ( n = 3 patients per group). ( C ) Representative dual-energy <t>x-ray</t> <t>absorptiometry</t> images of lumbar in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 vertebral <t>BMD</t> and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). ( D ) Representative dual-energy x-ray absorptiometry images of femur in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 femoral BMD and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). Data were analyzed by 2-way ANOVA ( B – D ). * P < 0.05; ** P < 0.01; *** P < 0.001. Data were presented as mean ± SD.
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( A ) Schematic diagram of patients with ESRD receiving intradialysis light aerobic exercise training ( n = 3 patients per group) or a nonexercise lifestyle ( n = 3 patients per group) for 12 weeks. An adjustable, bed-mounted treadmill was used as the training method. ( B ) Serum circulating irisin levels in resting or exercise-trained patients with ESRD at week 0 and week 12 ( n = 3 patients per group). ( C ) Representative dual-energy <t>x-ray</t> <t>absorptiometry</t> images of lumbar in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 vertebral <t>BMD</t> and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). ( D ) Representative dual-energy x-ray absorptiometry images of femur in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 femoral BMD and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). Data were analyzed by 2-way ANOVA ( B – D ). * P < 0.05; ** P < 0.01; *** P < 0.001. Data were presented as mean ± SD.
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( A ) Schematic diagram of patients with ESRD receiving intradialysis light aerobic exercise training ( n = 3 patients per group) or a nonexercise lifestyle ( n = 3 patients per group) for 12 weeks. An adjustable, bed-mounted treadmill was used as the training method. ( B ) Serum circulating irisin levels in resting or exercise-trained patients with ESRD at week 0 and week 12 ( n = 3 patients per group). ( C ) Representative dual-energy <t>x-ray</t> <t>absorptiometry</t> images of lumbar in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 vertebral <t>BMD</t> and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). ( D ) Representative dual-energy x-ray absorptiometry images of femur in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 femoral BMD and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). Data were analyzed by 2-way ANOVA ( B – D ). * P < 0.05; ** P < 0.01; *** P < 0.001. Data were presented as mean ± SD.
Bmds Smart Probes 7000 Series Reader, supplied by BioMedic Data Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


( A ) Schematic diagram of patients with ESRD receiving intradialysis light aerobic exercise training ( n = 3 patients per group) or a nonexercise lifestyle ( n = 3 patients per group) for 12 weeks. An adjustable, bed-mounted treadmill was used as the training method. ( B ) Serum circulating irisin levels in resting or exercise-trained patients with ESRD at week 0 and week 12 ( n = 3 patients per group). ( C ) Representative dual-energy x-ray absorptiometry images of lumbar in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 vertebral BMD and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). ( D ) Representative dual-energy x-ray absorptiometry images of femur in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 femoral BMD and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). Data were analyzed by 2-way ANOVA ( B – D ). * P < 0.05; ** P < 0.01; *** P < 0.001. Data were presented as mean ± SD.

Journal: JCI Insight

Article Title: Aerobic exercise prevents renal osteodystrophy via irisin-activated osteoblasts

doi: 10.1172/jci.insight.184468

Figure Lengend Snippet: ( A ) Schematic diagram of patients with ESRD receiving intradialysis light aerobic exercise training ( n = 3 patients per group) or a nonexercise lifestyle ( n = 3 patients per group) for 12 weeks. An adjustable, bed-mounted treadmill was used as the training method. ( B ) Serum circulating irisin levels in resting or exercise-trained patients with ESRD at week 0 and week 12 ( n = 3 patients per group). ( C ) Representative dual-energy x-ray absorptiometry images of lumbar in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 vertebral BMD and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). ( D ) Representative dual-energy x-ray absorptiometry images of femur in resting or exercise-trained patients. Red: area of osteodystrophy. Quantification of L2-L4 femoral BMD and BMD change rate in resting or exercise-trained patients at week 0, 4, 8, 12 ( n = 3 patients per group). Data were analyzed by 2-way ANOVA ( B – D ). * P < 0.05; ** P < 0.01; *** P < 0.001. Data were presented as mean ± SD.

Article Snippet: Demographic data were recorded at the time of enrollment, and the patients underwent BMD test by dual-energy x-ray absorptiometry (Excellus, OsteoSys) at weeks 0, 4, 8, and 12, and blood sampling at weeks 0, 2, 4, 8, and 12.

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